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  • We explore artificial-intelligence-assisted design and digital manufacturing of nanomaterials and nanodevices from nanoscale colloidal particles, wires and membranes as building blocks. We have invented a series of optical tools to sculpt and assemble the building blocks into functional architectures via computer programming. Inline metrology aided by artificial intelligence enables in-situ characterizations and feedback control for automated operations. 

  • Many of the basic molecular building blocks of life are chiral species, which are non-superimposable on their mirror images. We develop artificial-intelligence-enhanced chiroptical nanodevices to enable label-free enantiodiscrimination and enantioselective separation of chiral molecules. We are applying these devices to detect space life, to explore planet habitability, to study the origin and rules of life, to improve early disease diagnosis, and to enhance drug efficacy and safety. 

  • We develop light-powered autonomous nanorobots and lab-on-a-chip devices to bring healthcare diagnostics and therapy to underserved areas while advancing biosciences. Our robots and devices merge photonics, thermodynamics, fluidics and artificial intelligence at the nanoscale to interrogate, manipulate and dissect biological tissues, cells, bacteria, viruses, organelles and molecules at an unprecedented level.


We explore intelligent nanophotonics, which merges artificial intelligence and photonics at the nanoscale, to advance nanomanufacturing, global health and life sciencesOur mission is to:

  • improve fundamental understanding and control of light-matter interactions in complex nanosystems;
  • develop and apply artificial-intelligence-enhanced optical nanomaterials, nanodevices and nanotools; and 
  • promote interdisciplinary trainings for students to understand and contribute to the multiple fields of science, engineering and medicine.

  Principal Investigator:

  Yuebing Zheng
  Walker Department of Mechanical Engineering
  Materials Science and Engineering Program

Department of Electrical and Computer Engineering
  Department of Biomedical Engineering
  The University of Texas at Austin
  Austin, TX 78712, United States

  Phone: (512) 471-0228

Featured Research

Reconfigurable Chiral Metamolecules [Materials Today (2019)]

Opto-Thermoelectric Nanotweezers [Nature Photonics (2018)]

Opto-Thermophoretic Tweezers [ACS Nano (2017)]

Rewritable Nanophotonics [Nano Lett. 16 (2016) 7655]

Opto-Thermophoretic Assembly [ACS Nano 10 (2016) 9659]

Bubble-Pen Lithography [Nano Lett. 16 (2016) 701]